Publications of Lutz Nuhn

Nuhn, L.; Braun, L.; Overhoff, I.; Kelsch, A.; Schaeffel, D.; Koynov, K.; Zentel, R.: Degradable Cationic Nanohydrogel Particles for Stimuli-Responsive Release of siRNA. Macromolecular Rapid Communications 35 (24), pp. 2057 - 2064 (2014)

Nuhn, L.; Gietzen, S.; Mohr, K.; Fischer, K.; Toh, K.; Miyata, K.; Matsumoto, Y.; Kataoka, K.; Schmidt, M.; Zentel, R.: Aggregation Behavior of Cationic Nanohydrogel Particles in Human Blood Serum. Biomacromolecules 15 (4), pp. 1526 - 1533 (2014)

Nuhn, L.; Overhoff, I.; Sperner, M.; Kaltenberg, K.; Zentel, R.: RAFT-polymerized poly(hexafluoroisopropyl methacrylate)s as precursors for functional water-soluble polymers. Polymer Chemistry 5 (7), pp. 2484 - 2495 (2014)

Nuhn, L.; Tomcin, S.; Miyata, K.; Mailänder, V.; Landfester, K.; Kataoka, K.; Zentel, R.: Size-Dependent Knockdown Potential of siRNA-Loaded Cationic Nanohydrogel Particles. Biomacromolecules 15 (11), pp. 4111 - 4121 (2014)

Moers, C.; Nuhn, L.; Wissel, M.; Stangenberg, R.; Mondeshki, M.; Berger-Nicoletti, E.; Thomas, A.; Schaeffel, D.; Koynov, K.; Klapper, M. et al.; Zentel, R.; Frey, H.: Supramolecular Linear-g-Hyperbranched Graft Polymers: Topology and Binding Strength of Hyperbranched Side Chains. Macromolecules 46 (24), pp. 9544 - 9553 (2013)

Nuhn, L.; Hartmann, S.; Palitzsch, B.; Gerlitzki, B.; Schmitt, E.; Zentel, R.; Kunz, H.: Water-Soluble Polymers Coupled with Glycopeptide Antigens and T-Cell Epitopes as Potential Antitumor Vaccines. Angewandte Chemie, International Edition 52 (40), pp. 10652 - 10656 (2013)

Nuhn, L.; Schüll, C.; Frey, H.; Zentel, R.: Combining Ring-Opening Multibranching and RAFT Polymerization: Multifunctional Linear-Hyperbranched Block Copolymers via Hyperbranched Macro-Chain-Transfer Agents. Macromolecules 46 (8), pp. 2892 - 2904 (2013)

Nuhn, L.; Hirsch, M.; Krieg, B.; Koynov, K.; Fischer, K.; Schmidt, M.; Helm, M.; Zentel, R.: Cationic Nanohydrogel Particles as Potential siRNA Carriers for Cellular Delivery. ACS Nano 6 (3), pp. 2198 - 2214 (2012)

Schüll, C.; Nuhn, L.; Mangold, C.; Christ, E.; Zentel, R.; Frey, H.: Linear-Hyperbranched Graft-Copolymers via Grafting-to Strategy Based on Hyperbranched Dendron Analogues and Reactive Ester Polymers. Macromolecules 45 (15), pp. 5901 - 5910 (2012)

Siegwart, D. J.; Whitehead, K. A.; Nuhn, L.; Sahay, G.; Cheng, H.; Jiang, S.; Ma, M.; Lytton-Jean, A.; Vegas, A.; Fenton, P. et al.; Levins, C. G.; Love, K. T.; Lee, H.; Cortez, C.; Collins, S. P.; Li, Y. F.; Jang, J.; Querbes, W.; Zurenko, C.; Novobrantseva, T.; Langer, R.; Anderson, D. G.: Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery. Proceedings of the National Academy of Sciences of the United States of America 108 (32), pp. 12996 - 13001 (2011)

Kaps, L.; Huppertsberg, A.; Choteschovsky, N.; Klefenz, A.; Durak, F.; Schoers, B.; Diken, M.; Eichler, E.; Rosigkeit, S.; Schmitt, S. et al.; Leps, C.; Foerster, F.; Bockamp, E.; Degeest, B.; Marini, F.; Koynov, K.; Tenzer, S.; Schuppan, D.; Nuhn, L.: Bisphosphonate-loaded nanogels attentuate liver fibrosis by repolarization of M2-type macrophages. In Journal of Hepatology, 77 (Supplement 1), FRI147, p. S464 - S464. Elsevier, Amsterdam (2022)

Medina-Montano, C.; Stickdorn, J.; Haist, M.; Nuhn, L.; Bros, M.; Grabbe, S.: Biological effects of systemically administered TLR7/8 Agonist and Antigen-conjugated nanogels on immune cell populations. In European Journal of Immunology, 52 S1 Ed., P246, pp. 366 - 367. Joint Meeting of the German Society for Immunology (DGfl) and the Austrian Society for Allergology & Immunology (ÖGAI), Hannover, Germany, September 07, 2022 - September 10, 2022. Wiley-VCH, Weinheim (2022)

Hahlbrock, J.; Arnold-Schild, D.; Stickdorn, J.; Ziss, T.; Bros, M.; Grabbe, S.; Nuhn, L.; Schild, H.: Polymer-mediated tumour immunotherapy by in situ activation of antigen presenting cells. In European Journal of Immunology, 49 (SI) 1 Ed., O116, p. 72 - 72. 2nd Joint Meeting of the German-Society-for-Immunology (DGfl) and the Italian-Society-of-Immunology-Clinical-Immunology-and-Allergology (SIICA), Munich, Germany, September 10, 2019 - September 13, 2019. Wiley-VCH, Weinheim (2019)

Kaps, L.; Nuhn, L.; Choteschovsky, N.; Klefenz, A.; Aslam, M. J.; Zentel, R.; Schuppan, D.: NANOPARTICULAR BISPHOSPHONATE TO SELECTIVELY TARGET AND REPOLARIZE LIVER MACROPHAGES FOR ANTI-FIBROTIC RESPONSES IN experimental LIVER FIBROSIS. In Hepatology, 70 (S1), 1877, p. 1127A - 1127A. Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, Boston, MA, November 08, 2019 - November 12, 2019. Wiley (2019)

Kaps, L.; Schuppan, D.; Nuhn, L.; Ashfaq-Khan, M.; Aslam, M.; Klefenz, A.; Choteschovsky, N.: Nanoparticular bisphosphonate to selectively target and repolarize liver macrophages for efficient anti-tumour response. In Journal of Hepatology, 70 (1, Supplement), THU-469, pp. E366 - E367. International Liver Congress, Vienna, AUSTRIA, April 10, 2019 - April 14, 2019. Elsevier, Amsterdam (2019)

Nuhn, L.; De Geest, B.: Intracellular unfolding nanoparticles for the delivery of immune-stimulatory cues towards anticancer immunity. In Abstracts of Papers of the American Chemical Society, 253 (PMSE), 636. 253rd ACS National Meeting , San Francisco, CA, March 30, 2017 - April 07, 2017. (2017)

De Coen, R.; Nuhn, L.; De Geest, B.: Acid-degradable, mannosylated nanogels for dendritic cell targeting. In Abstracts of Papers of the American Chemical Society, 251 (PMSE), 118. 251st ACS National Meeting, San Diego, CA, March 13, 2016 - March 17, 2016. (2016)

Kaps, L.; Leber, N.; Aslam, M.; Brose, A.; Nuhn, L.; Schupp, J.; Zentel, R.; Schuppan, D.; Tuttenberg, A.; Diken, M.: In vivo gene silencing in the liver: Comparison of siRNA-loaded non biodegradable vs. biodegradable nanohydrogel particles for antifibrotic therapy. In Hepatology, 64 (S1), 217, p. 115A - 115A. 67th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), Boston, MA, November 11, 2016 - November 15, 2016. Wiley - American Association for the Study of Liver Diseases (2016)

Kaps, L.; Nuhn, L.; Aslam, M.; Brose, A.; Foerster, F.; Zentel, R.; Schuppan, D.: In Vivo Myofibroblast Specific Gene Silencing in the Liver Using Novel Sirna-Loaded Biodegradable Nanohydrogel Particles. In Journal of Hepatology, 64 (S2), FRI-015, p. S448 - S448. EASL International Liver Congress, Barcelona, Spain, April 13, 2016 - April 17, 2016. Elsevier, Amsterdam (2016)

Nuhn, L.; Leber, N.; Zentel, R.: Cationic nanohydrogel particles as carriers for therapeutic oligonucleotide delivery. In Abstracts of Papers of the American Chemical Society, 251 (POLY), 512. 251st ACS National Meeting, San Diego, CA, March 10, 2016 - March 18, 2016. (2016)