BBFlow - A flow-model to predict how proteins move

April 02, 2025

Wondering how to predict protein flexibility in only a second? No time to run MD simulations but want to go beyond pLDDT? Check out BBFlow!


BBFlow is particularly useful for de novo designs, that is, when one lacks sequence information.
Lead by Nicolas Wolf and Leif Seute, with Seva Viliuga, Simon Wagner and Jan Stuehmer.

Nicolas Wolf, Leif Seute, Vsevolod Viliuga, Simon Wagner, Jan Stühmer, Frauke Gräter.
Learning conformational ensembles of proteins based on backbone geometry
arXiv:2503.05738v1 [q-bio.BM] (2025)

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